Experts share their picks for the Patriots Week 6 matchup against the Kansas City Chiefs.

Mike Reiss, ESPN:

Pick: Patriots 41, Chiefs 27

History says the Patriots should be in a good place, as under-25 starting quarterbacks are a combined 0-23 on the road in the regular season against New England since 2001. Tom Brady (41) is 18 years, 45 days older than Patrick Mahomes (23), which according to Elias Sports Bureau research makes this the largest age difference between opposing starting quarterbacks since Matt Hasselbeck faced Jameis Winston in 2015 (they were 18 years, 103 days apart). The Patriots should be able to move the ball and score points on the Chiefs' defense.

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Mike Golic, ESPN: Patriots

Seth Wickersham, ESPN: Patriots

Mina Kimes, ESPN: Chiefs

Trey Wingo, ESPN: Patriots

Pete Prisco, CBS Sports:

Pick: Patriots 27, Chiefs 20

This is the game of the week with the undefeated Chiefs facing the Patriots. The Chiefs looked better on defense last week against Jacksonville, but I think the Patriots run through them in this one. Patrick Mahomes will be limited by the schemes of Bill Belichick here and the Patriots will win it.

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Jason La Canfora, CBS Sports: Patriots

Will Brinson, CBS Sports: Chiefs

Dave Richard, CBS Sports: Patriots

Ryan Wilson, CBS Sports: Chiefs

Elliot Harrison, NFL.com:

Pick: Patriots 34, Chiefs 30

Patrick Mahomes will have a chance to strut his already mature game in front of a national audience once again in what should be a gem of a Sunday-nighter. Tom Brady should go toe-to-toe, er, arm-to-arm with the Chiefs sophomore QB. With Julian Edelman back, Josh Gordon picking up the offense and Sony Michel providing at least the threat of balance, we're staring at an explosive matchup ... on paper, anyway. Justin Houston's likely absence makes it more so, as Brady will be able to pat, pat and pat the ball some more until somebody breaks open. Kansas City's pass rush is oft-absentee, and I'm not talking about ballots. Yes, they have accumulated a healthy number of sacks, but nobody is throwing the ball more than the Chiefs' opponents (well, except for Andrew Luck). That's why involving Kareem Hunt early and often makes sense, much like last year's kickoff game. In case you don't remember ...

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Mike Florio, Pro Football Talk:

Pick: Chiefs 34, Patriots 31

Bill Belichick likes to take away what the opposing offense does best. Rarely does he face an offense that does everything best.

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Michael David Smith, Pro Football Talk:

Pick: Chiefs 24, Patriots 21

The best matchup of the week is on Sunday night, and I think the Chiefs will prove they're the class of the AFC.

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Paul Perillo, Patriots.com:

Pick: Patriots 38, Chiefs 34

Patriots win track meet thanks to a couple of mistake by Mahomes.

Andy Hart, Patriots.com:

Pick: Chiefs 35, Patriots 31

Too much speed and too many red-hot Kansas City playmakers for the Patriots to keep up with.

Erik Scalavino, Patriots.com:

Pick: Patriots 42, Chiefs 41

Games like this don't always live up to the hype - but this one will. It will come down to either the defense or special teams making a play at the end to determine the outcome.