Week 1 vs. Houston Texans
The defense contained Deshaun Watson and the Texans in a 27-20 win to open the season.

Week 2 at Jacksonville Jaguars
Jacksonville controlled the game from start to finish and came away with a 31-20 victory over the Patriots.

Week 3 at Detroit Lions
New England dropped their second road game of the season with the Lions utilizing a ball-control attack to the tune of a 26-10 victory over the Patriots.

Week 4 vs. Miami Dolphins
The Patriots snapped their two-game losing streak with a dominant 38-7 victory over the Miami Dolphins.

Week 5 vs. Indianapolis Colts
Tom Brady's 500th career touchdown secured a 38-24 victory over the undermanned Indianapolis Colts.

Week 6 vs. Kansas City Chiefs
Both offenses dominated in the Sunday night showdown as the Patriots outlasted the Chiefs, 43-40.

Week 7 at Chicago Bears
Special teams lead the way in the Patriots 38-31 win in Chicago.

Week 8 at Buffalo Bills
The Patriots defense led the way in a Monday night 25-6 win in Buffalo.

Week 9 vs Green Bay Packers
The defense continued its solid play in the Patriots 31-17 win over Green Bay.

Week 10 at Tennessee Titans
New England struggles on both sides of the ball in upset 34-10 loss to Titans.

Week 12 at New York Jets
New England comes out of the bye with a hard-fought 27-13 road win over the Jets.

Week 13 vs Minnesota Vikings
The defense turned in its best performance of the year in New England's 24-10 victory over the Vikings.

Week 14 at Miami Dolphins
Miami's miracle finish in the final seconds of the game leads to 34-33 loss to the Dolphins.

Week 15 at Pittsburgh Steelers
New England comes up short on the road for the second straight week with a 17-10 loss to the Steelers.

Week 16 vs. Buffalo Bills: W 24-12
New England returned home and got the ground game going to dispose of Buffalo, 24-12 and clinch the AFC East title.

Week 17 vs. New York Jets
New England closes out perfect home regular season record with a dominant 38-3 victory over the Jets.