Kansas City Chiefs running back Priest Holmes is expected to retire after suffering another neck injury Sunday and meeting with doctors this week. An announcement could come as early as Wednesday.

One source familiar with the situation said Tuesday night: "He is retiring for sure. Noon press conference on Wednesday."

However, a Chiefs spokesman denied that and said that Holmes still is weighing his options.

A three-time Pro Bowler, Holmes was one of the league's top running backs from 2001-05, rushing for almost 6,000 yards and scoring a then-record 27 touchdowns in 2003. His career appeared to be over when he sustained neck and spinal injuries during a game at San Diego in October 2005 and spent the next two years completely away from the game.

But he called the Chiefs shortly before they went to training camp in July and told them he had seen himself in a dream playing football again and wanted to stage a comeback.

Holmes capped a remarkable comeback story when he was activated in Week 7 against the Oakland Raiders. Holmes made two recent starts for the Chiefs and gained 137 yards on 46 attempts in four games.

Holmes would retire as the Chiefs' all-time leading rusher with 6,070 yards. He has rushed for 8,172 yards in his 11-year career with Baltimore and Kansas City.

The Chiefs, who traded running back Michael Bennett to Tampa Bay last month and possibly lost Larry Johnson for the season with a mysterious foot injury, could turn to rookie Kolby Smith to start against the Raiders on Sunday. Smith, a fifth-round selection out of Louisville, has rushed for 19 yards on 10 attempts this season.