Gronk is back! The Patriots tight end is once again the most dominant mismatch in the NFL and will test the suspect middle of the Colts pass defense like no weapon has previously.

Browner has three games under his belt and his physical style has been obvious. He'll certainly be challenged by Andrew Luck and a very deep, versatile cast of Colts weapons.

Indy has the ability to attack a pass defense all across the field. New England's safeties will have to deal with impressive tight end Dwayne Allen and highly effective pass-catching back Ahmad Bradshaw, among others.

There is a good chance this big AFC battle with the Colts could come down to the wire. If that's the case Gostkowski's strong, accurate leg might get a chance for a game-winner.

The Colts have the league's top scoring attack thanks to the third-year star Luck. It will be old No. 12 vs. young No. 12 and that should lead to a lot of points being scored in a Brady vs. Luck III.

The Colts safety has been thrust into action on defense rather than his more productive role on special teams. Brown was a defensive liability early in his career in New England and Brady should treat him as such this Sunday night.

Bradshaw is averaging 5.1 yards a carry and has six touchdown catches. The former Giant will test the Patriots linebackers and safeties on all three downs.

The former New England Super Bowl legend continues to prove himself a dominant kicker in Indy. Vinatieri hasn't missed a field goal this year and it's not hard envisioning him nailing a key kick in this battle for AFC positioning.

Allen didn't play in the postseason battle last January and certainly gives Luck a very productive force in the passing game. The tight end has a team-high seven touchdown catches and will be another challenge for the middle of the Patriots secondary.